Prof. Dr. C. Höbartner - THE HÖBARTNER GROUP: ORGANIC AND BIOMOLECULAR CHEMISTRY

Prof. Dr. Claudia Höbartner

Universität Würzburg
Institut für Organische Chemie and
Center for Nanosystems Chemistry
Am Hubland
97074 Würzburg

Phone: +49 931 31-89693
Fax: +49 931 31-84755
claudia.hoebartner@uni-wuerzburg.de

Office Administration

Eleonore Klaus

Phone: +49 931 31-85322
l-oc1.chemie@uni-wuerzburg.de
eleonore.klaus@uni-wuerzburg.de

Welcome

Explore with us the exciting chemistry of nucleic acids! We synthesize chemically modified DNA and RNA, develop DNA catalysts, ribozymes and RNA aptamers, and explore their functions and innovative applications at the interface of chemistry and biology.

Just Published

H.-A. Chen, T. Okuda, A-K. Lenz, C. P. M. Scheitl, H. Schindelin, C. Höbartner. "Structure and catalytic activity of the SAM utilizing ribozyme SAMURI" Nature Chemical Biology 2025, published online January 8

J. Kuper, T. Hove, S. Maidl, H. Neitz, F. Sauer, M. Kempf, T. Schroeder, E. Greiter, C. Höbartner & C. Kisker. "XPD stalled on cross-linked DNA provides insight into damage verification", Nature Structural and Molecular Biology 2024, published online May 28

I. Bessi, C. Stiller, T. Schroeder, B. Schäd, M. Grüne, J. Dietzsch, C. Höbartner, The Tautomeric State of N⁴-Hydroxycytidine within Base-Paired RNA, ACS Cent. Sci. 2024, published online April 25

For more papers, please visit our page "publications"

Further information about our research:

Video Gottfried Wilhelm Leibniz Prize 2023

Video Hansen Family Award 2023

News

Dr Takumi Okuda gave a presentation at the 2nd International Symposium on Chemical Biology (EFMC-ISCB) in Basel, Switzerland

"From January 29th to 31st, the 2nd International Symposium on Chemical Biology (EFMC-ISCB) was held in Basel, Switzerland. This conference brought together researchers from academia and industry to discuss a wide range of topics related to chemical…

more

Konstantin Isenberg attended the Chemical Biology conference 2025 on 21th - 22th January in Frankfurt

The Advances in Chemical Biology 2025 conference, held in Frankfurt, brought together researchers, scientists, and industry professionals from around the world to discuss the latest developments and innovations in drug discovery, bioimaging, and…

more

Behind the scenes — from construct design to SAMURI 3D structures

Crystal structures of the SAM-utilizing ribozyme, SAMURI, were decoded, revealing the structural features that distinguishes itself from SAM riboswitches and thus enables the alkyl transfer reactions.

more

Hubland Süd, Geb. C1

Picture credits