Prof. Dr. C. Höbartner

Prof. Dr. Claudia Höbartner

Universität Würzburg
Institut für Organische Chemie and
Center for Nanosystems Chemistry
Am Hubland
97074 Würzburg

Phone: +49 931 31-89693
Fax: +49 931 31-84755
claudia.hoebartner@uni-wuerzburg.de

Office Administration

Eleonore Klaus

Phone: +49 931 31-85322
l-oc1.chemie@uni-wuerzburg.de
eleonore.klaus@uni-wuerzburg.de

Welcome

Explore with us the exciting chemistry of nucleic acids! We synthesize chemically modified DNA and RNA, develop DNA catalysts, ribozymes and RNA aptamers, and explore their functions and innovative applications at the interface of chemistry and biology.

Further information about our research:

Video Gottfried Wilhelm Leibniz Prize 2023

Video Hansen Family Award 2023

Just Published

J. Kuper, T. Hove, S. Maidl, H. Neitz, F. Sauer, M. Kempf, T. Schroeder, E. Greiter, C. Höbartner & C. Kisker. "XPD stalled on cross-linked DNA provides insight into damage verification", Nature Structural and Molecular Biology 2024, published online May 28

I. Bessi, C. Stiller, T. Schroeder, B. Schäd, M. Grüne, J. Dietzsch, C. Höbartner, The Tautomeric State of N⁴-Hydroxycytidine within Base-Paired RNA, ACS Cent. Sci. 2024, published online April 25, 2024

C. Höbartner, K.E. Bohnsack, M.T. Bohnsack. How Natural Enzymes and Synthetic Ribozymes Generate Methylated Nucleotides in RNA. Annu Rev Biochem. 2024 Apr 10.

F. Seitz, T. Jungnickel, N. Kleiber, J. Kretschmer, J. Adelmann, J. Dietzsch, K.E. Bohnsack, M.T. Bohnsack, C. Höbartner. Atomic mutagenesis of N⁶-methyladenosine reveals distinct recognition modes of human m⁶A reader and eraser proteins J. Am. Chem. Soc. 2024, published online March 6

M. Müller, H. Neitz, C. Höbartner, H. Helten, BN-Phenanthrene- and BN-Pyrene-Based Fluorescent Uridine Analogues. Org. Lett. 2024, Jan 29.

J. Dietzsch, A. Jayachandran, S. Mueller, C. Höbartner, T. Brixner, Excitonic coupling of RNA-templated merocyanine dimer studied by higher-order transient absorption spectroscopyChem. Commun. 2023, May 23.

News

Bavarian Culture Prize for chemist Carolin Scheitl

Dr. Carolin Scheitl, a researcher at the University of Würzburg, was awarded the Bavarian Culture Prize in the science category for her doctoral thesis on RNA chemistry.

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A warm welcome to Arijit Das Adhikary

We are pleased to welcome Arijit Das Adhikary from IIT Bombay as a visiting PhD student at our research group for the next two months.

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GDCh Biochemistry 2024 - New Frontiers in Chemical Biology and Biochemistry

On 1st October 2024, Dr. Carolin Scheitl gave a talk at the "GDCh Biochemistry 2024 (September 30th - October 2nd 2024), Dortmund, Germany" about the topic "Ribozymes for RNA labelling via adenosine alkylation".

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