DNA probing
Probing and minimization of functional DNA
Selected publications on combinatorial probing
F. Javadi-Zarnaghi, C. Höbartner, Functional hallmarks of a catalytic DNA that makes lariat RNA.
Chem. Eur. J. 2016, 22, 3720-3726.
K. Wawrzyniak-Turek, C. Höbartner, Enzymatic combinatorial nucleoside deletion scanning mutagenesis of functional RNA. Chem. Commun. 2014, 50, 10937-10940.
B. Samanta, C. Höbartner, Combinatorial Nucleoside-Deletion-Scanning Mutagenesis of Functional DNA. Angew. Chem. Int. Ed. 2013, 52, 2995-2999. Angew. Chem. 2013, 125, 3069-3073.
F. Wachowius, C. Höbartner, Probing essential nucleobase functional groups in aptamers and deoxyribozymes by nucleotide analog interference mapping of DNA. J. Am. Chem. Soc. 2011, 133, 14888-14891.
F. Wachowius, F. Javadi-Zarnaghi, C. Höbartner, Combinatorial Mutation Interference Analysis reveals functional nucleotides required for DNA catalysis. Angew. Chem. Int. Ed. 2010, 49, 8504-8508. Angew. Chem. 2010, 122, 8682-8687.
