Research

The Wencel-Delord Research Group is dedicated to advancing the frontiers of organic synthesis through the development of innovative catalytic strategies. Our research focuses on pioneering hypervalent bromine chemistry, utilizing cutting-edge techniques such as photocatalysis, transition metal catalysis, and organocatalysis to address key challenges in modern organic synthesis.

A central theme of our work is the exploration of light-driven C-H functionalization methodologies, enabling the formation of C-C, C-N, and C-O bonds. These transformations, including asymmetric processes, are applied to a broad range of substrates, from simple feedstocks to complex molecules and advanced materials. One of our primary objectives is to leverage these methodologies for the synthesis of natural products, bioactive compounds, and materials with high relevance in various industries.

In addition to synthetic innovation, we are deeply invested in understanding the underlying mechanisms of these catalytic processes. Through detailed physical organic chemistry studies and computational approaches, including density functional theory (DFT) calculations, we aim to unravel the principles governing these reactions. This mechanistic insight not only enhances our fundamental knowledge but also supports the broader application of these novel catalytic systems in both academic research and industrial settings.

Our group also extends its expertise beyond the lab bench, collaborating on engineering projects that focus on photoredox and C-H activation for the scalable synthesis of fine chemicals. These efforts aim to bridge the gap between cutting-edge catalysis and practical, industrial-scale applications.