Intern
    Prof. Dr. Reinhold Tacke

    Disila-bexarotene

      

    Disila-Analogues of the Retinoid Agonist Bexarotene

    Synthesis of Disila-bexarotene

    Superposition of the Tetraline and Disila-tetraline Skeleton

     

    Electrostatic Potentials Mapped on the Calculated Isosurfaces of the Electron Density

     

    RXRβ Receptor Activation

    Patents:

    J. G. Montana, A. G. Showell, I. Fleming, R. Tacke, J. Daiss (Inventors), Amedis Pharmaceuticals Ltd., Cambridge, U.K., PCT Int. Pat. Appl. WO 2004/048390 A1 (10.06.2004). more ...

    J. G. Montana, G. A. Showell, R. Tacke (Inventors), Amedis Pharmaceuticals Ltd., Cambridge, U.K., PCT Int. Pat. Appl. WO 2004/048391 A1 (10.06.2004). more ...

    Publications:

    J. O. Daiss, C. Burschka, J. S. Mills, J. G. Montana, G. A. Showell, I. Fleming, C. Gaudon, D. Ivanova, H. Gronemeyer, R. Tacke, Organometallics 2005, 24, 3192–3199.  more ...

    M. W. Büttner, M. Penka, L. Doszczak, P. Kraft, R. Tacke, Organometallics 2007, 26, 1295–1298. more ...

    M. W. Büttner, J. B. Nätscher, C. Burschka, R. Tacke, Organometallics 2007, 26, 4835–4838. more ...