Spin-labeled RNA
Rigid spin labels for EPR spectroscopy of RNA
Selected publications on spin-labeled RNA
K. Halbmair, J. Seikowski, I. Tkach, C. Höbartner, D. Sezer, M. Bennati, High-resolution measurement of long-range distances in RNA: pulse EPR spectroscopy with TEMPO-labeled nucleotides. Chem. Sci. 2016, 7, 3172-3180.
L. Büttner, F. Javadi-Zarnaghi, C. Höbartner, Site-specific labeling of RNA at internal ribose hydroxyl groups: terbium-assisted deoxyribozymes at work. J. Am. Chem. Soc. 2014, 136, 8131-8137.
K. Wawrzyniak-Turek, C. Höbartner, Deoxyribozyme-mediated ligation for incorporating EPR spin labels and reporter groups into RNA. Methods Enzymol. 2014, 549, 85-104.
L. Büttner, J. Seikowski, K. Wawrzyniak, A. Ochmann, C. Höbartner, Synthesis of spin-labeled riboswitch RNAs using convertible nucleosides and DNA-catalyzed RNA ligation. Bioorg. Med. Chem. 2013, 21, 6171-6180.
C. Höbartner*, G. Sicoli, F. Wachowius, D.B. Gophane, S.T. Sigurdsson*, Synthesis and Characterization of RNA Containing a Rigid and Nonperturbing Cytidine-Derived Spin Label. J. Org. Chem. 2012, 77, 7749-7754.
